AB1038 RELATIONSHIP BETWEEN ANKYLOSIS AND PHYSICAL FUNCTION ASSESSMENT IN ANKYLOSING SPONDYLITIS

Background Ankylosing spondylitis (AS) is a progressive inflammatory disease affecting the spine and large joints of extremities. Ankylosis sacroiliac affects patients not only physically but also psychologically socially, resulting in significant decline quality life (QOL) disruption daily activities [1]. However, it unclear to what extent progression physical function patient subjective evaluation. Objectives The purpose this study was investigate relationship between degree ankylosis, function, frailty with AS. Methods Twenty-four AS attending our hospital who underwent full computer tomography (CT) assessment were included study. anterior-posterior, intervertebral joint, interspinous process ankylosis sites number (whole spine/cervical spine/thoracic spine/lumbar spine) joint evaluated each vertebra. Patient-objective measures gait speed, grip strength, Timed Up Go test (TUG), time five sit-to-stand, Bath Spondylitis Metrology Index (BASMI), patient-subjective Functional (BASFI), Kihon Checklist (KCL), 25-question Geriatric Locomotive Function Scale (GLFS-25), Beck Depression Inventory (BDI-II) as assessments. Spearman’s rank correlation coefficient used analyze items. Results mean age (± standard deviation) at 40±15 years, 79% male, 50% HLA-B27 positive, duration 13±9 years. Age significantly correlated thoracic (r=0.449), total spine/sacroiliac (r=0.600/0.553/0.635/0.510). BASMI, an objective assessment, showed (r=0.732/0.653/0.707/0.615), walking TUG, or sit-to-stand. BASFI, spine/ cervical lumbar ankylosis(r=0.680/0.729/0.600/0.469), GLFS-25 (r=0.418/0.500) ankylosis. BDI-II, psychiatric symptoms, KCL, frailty, no Conclusion BASFI GLFS-25, assessments, spinal patients, found interfere life. Reference [1]Braun J, Sieper J. spondylitis. Lancet. 2007;369(9570):1379-90. Acknowledgements: NIL. Disclosure Interests None Declared.